Increased circulating heat shock protein 70 levels in pregnant asthmatics
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چکیده
منابع مشابه
Anti-Heat Shock Protein 70 antibody levels are increased in myasthenia gravis and Guillain-Barré syndrome.
Myasthenia gravis (MG) is an autoimmune disorder where patients develop autoantibodies towards skeletal muscle proteins (e.g. acetylcholine receptor and muscle specific kinase), causing weakness in striated muscles. Ocular MG (OMG) represents a subtype of (MG) affecting only the periocular muscles. The pathogenesis of this phenotype remains unclear. Heat Shock Protein 70 (Hsp70) plays a role in...
متن کاملIncreased expression of heat shock protein-binding protein 1 and heat shock protein 70 in human hepatocellular carcinoma tissues.
Heat shock protein-binding protein 1 (HspBP1) is a co-chaperone that inhibits heat shock 70-kDa protein (Hsp70) activity. In mouse neuroblastomas and lung tumors, the protein levels of HspBP1 and Hsp70 are elevated by a similar amount compared to non-tumor tissues. However, no studies have been reported regarding the levels of HspBP1 in human cancer tissues. Our previous proteomic study demonst...
متن کاملHeat Shock Protein 70 in Alzheimer's Disease
Alzheimer's disease (AD) is the most common neurodegenerative disease that caused dementia which has no effective treatment. Growing evidence has demonstrated that AD is a "protein misfolding disorder" that exhibits common features of misfolded, aggregation-prone proteins and selective cell loss in the mature nervous system. Heat shock protein 70 (HSP70) attracts extensive attention worldwide, ...
متن کاملEvaluation of Salivary Level of Heat Shock Protein 70 in Patients with Breast Cancer
Introduction: Breast cancer is the most common cancer diagnosed among women worldwide. Increased molecular and genetic information about cancer has improved diagnostic, screening, and treatment methods for cancer. Heat shock protein 70 (HSP70) is overexpressed in breast cancer patients and involved in malignant properties of breast cancer. Due to the noninvasive nature of saliva collection and ...
متن کاملHeat shock protein 70 and anti–heat shock protein 70 antibodies in nasal secretions of patients with chronic rhinosinusitis
BACKGROUND The issue of heat shock protein (HSP) 70 and anti-HSP70 antibodies in chronic rhinosinusitis (CRS) has never been explored. OBJECTIVE To determine the nasal secretion (NS) levels of HSP70 and anti-HSP70 antibodies in patients with CRS with nasal polyps (CRSwNP) and patients with CRS without nasal polyps (CRSsNP), and to evaluate their associations with CRS clinical severity and cor...
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ژورنال
عنوان ژورنال: Cell Stress and Chaperones
سال: 2009
ISSN: 1355-8145,1466-1268
DOI: 10.1007/s12192-009-0143-8